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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RRN3
All Species:
19.09
Human Site:
T292
Identified Species:
35
UniProt:
Q9NYV6
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NYV6
NP_060897.3
651
74107
T292
N
M
D
E
D
E
E
T
E
H
E
T
K
A
G
Chimpanzee
Pan troglodytes
XP_001143837
595
67943
Y268
L
M
S
L
V
L
S
Y
M
K
D
V
C
Y
V
Rhesus Macaque
Macaca mulatta
XP_001108222
651
74080
T292
N
M
D
E
D
E
E
T
E
H
D
T
K
A
G
Dog
Lupus familis
XP_536965
651
74211
T292
N
M
D
E
D
E
D
T
E
R
D
T
K
A
D
Cat
Felis silvestris
Mouse
Mus musculus
B2RS91
656
74499
T290
N
M
D
E
D
E
D
T
D
P
E
K
K
A
D
Rat
Rattus norvegicus
NP_001129318
661
75125
T290
N
M
D
E
D
E
E
T
D
P
E
K
K
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518561
660
75690
T301
E
M
D
E
D
E
E
T
N
G
D
V
K
G
T
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001107876
612
69642
M270
T
P
V
V
S
E
S
M
A
H
P
V
A
E
R
Zebra Danio
Brachydanio rerio
XP_706962
612
68744
M270
S
G
A
D
G
G
A
M
V
H
P
V
A
E
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_788084
611
70731
K275
V
C
A
E
N
V
P
K
S
E
K
S
V
S
H
Honey Bee
Apis mellifera
XP_001122533
483
56793
H157
I
I
H
E
T
H
T
H
E
V
Y
V
Y
A
L
Nematode Worm
Caenorhab. elegans
P48322
654
75091
N277
I
E
E
V
V
E
G
N
T
N
D
S
E
D
V
Sea Urchin
Strong. purpuratus
XP_784172
374
42533
A48
K
V
K
L
S
E
K
A
T
K
V
D
T
L
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.4
97.6
90.6
N.A.
86.8
85.4
N.A.
76
N.A.
66.8
59.9
N.A.
29.7
27.7
24.4
28.5
Protein Similarity:
100
89
99
94.7
N.A.
92.9
91.8
N.A.
86
N.A.
79.8
76
N.A.
48.8
46.3
42.8
40.7
P-Site Identity:
100
6.6
93.3
73.3
N.A.
66.6
73.3
N.A.
53.3
N.A.
13.3
6.6
N.A.
6.6
20
6.6
6.6
P-Site Similarity:
100
13.3
100
86.6
N.A.
80
80
N.A.
60
N.A.
13.3
20
N.A.
33.3
26.6
40
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
0
0
0
8
8
8
0
0
0
16
47
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
47
8
47
0
16
0
16
0
39
8
0
8
16
% D
% Glu:
8
8
8
62
0
70
31
0
31
8
24
0
8
16
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
8
8
8
0
0
8
0
0
0
8
16
% G
% His:
0
0
8
0
0
8
0
8
0
31
0
0
0
0
8
% H
% Ile:
16
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
8
0
8
0
0
0
8
8
0
16
8
16
47
0
0
% K
% Leu:
8
0
0
16
0
8
0
0
0
0
0
0
0
8
8
% L
% Met:
0
54
0
0
0
0
0
16
8
0
0
0
0
0
8
% M
% Asn:
39
0
0
0
8
0
0
8
8
8
0
0
0
0
0
% N
% Pro:
0
8
0
0
0
0
8
0
0
16
16
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
16
% R
% Ser:
8
0
8
0
16
0
16
0
8
0
0
16
0
8
0
% S
% Thr:
8
0
0
0
8
0
8
47
16
0
0
24
8
0
8
% T
% Val:
8
8
8
16
16
8
0
0
8
8
8
39
8
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
8
0
8
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _